Darier disease cells lose antioxidant defenses under stress, study finds
Repercussão envolvendo Northwestern Medicine chama atenção em Fitness.
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In vivo CRISPR screen identifies gene edits that strengthen CAR-T therapy against solid tu
For patients with blood cancers like leukemia and lymphoma, the immunotherapy known as CAR-T cell therapy can be lifesaving. Doctors remove a patient's immune cells, called T cells, engineer them in the lab to better recognize and attack cancer, and infuse them back into the bloo
Drug-carrying nanoparticles shrink venous malformations by 70% in mice
Venous malformations are abnormally shaped veins that develop when the cells lining blood vessels grow too fast when they aren't supposed to. Destaque: 70%.
Space travel doesn't affect the strength of heart muscle cells, study finds
It's common to see images of astronauts on the International Space Station exercising, running on special treadmills and pedaling cycles designed for tight quarters.
Cancer protein p53 observed in action reveals more order than expected
Cancer occurs when cells divide uncontrollably and displace healthy cells.
AI maps tumor cells that may seed later metastases
A cancerous tumor is not a single enemy.
Cortical organoids mirror mouse brain cell types, yet lose developmental sequence
Over a decade ago, scientists redefined how to study organ development by generating seemingly unremarkable clumps of cells.
Scientists find evidence for two origins of life on Earth
Scientists probing life’s deepest origins have uncovered evidence that the first free-living cells may have emerged not once, but twice.
Quality control of proteins in the cellular membrane starts at the ribosome
Scientists at the Center for Molecular Medicine Cologne (CMMC) and the CECAD Cluster of Excellence on Aging Research have demonstrated in a biomedical study that ribosomes, the protein factories of our cells, face an unusually tough challenge when building large, membrane-embedde
Fluorescence lifetime imaging distinguishes multiple proteins in living plant cells
Fluorescent protein imaging is an indispensable tool in life science research, enabling visualization of protein movement and localization, gene expression, signaling pathways, protein-protein interactions and more.
‘A mouse can’t tell us what works’: UK scientists to grow miniature human organs for drug testing
Organoids and tissues grown from human cells promise more accurate results, with £20m Cambridge project to create standardised modelsMiniature human organs and other tissues are to be grown from NHS patients’ cells in a drive to improve medicine testing and reduce the number of a
Stem cells create humanlike heart valve tissue to model disease and test treatments
Melbourne researchers have created human heart valve tissues from stem cells, providing a powerful new platform to advance treatments for childhood heart diseases.